Download BLTR: the Leukotriene B4 Receptor by Luster A.D., Tager A.M. PDF
By Luster A.D., Tager A.M.
The receptor for leukotriene B4 (LTB4). BLTR. is a member of the G prolein-coupled seven transmembrane area receptor (GPCR) superfamily. This receptor is extremely expressed on leukocytes, and mediates LTB4-induced leukocyte chemotaxis and activation. BLTR for that reason participates within the recruitment of leukocytes to websites of pathogen invasion as a part of the innate immune reaction, and likewise within the pathogenesis of inflammatory reactions during which LTB4 has been implicated. BLTR antagonists have effectively diminished leukocyte recruitment and tissue harm in animal types of inflammatory ailments, demonstrating the healing power of inhibiting BLTR within the remedy of pathologic irritation.
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Extra resources for BLTR: the Leukotriene B4 Receptor
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